Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional regulation of the type I myosin heavy chain gene in denervated rat soleus.

American journal of physiology. Cell physiology - 1 Mar 2003

Huey K A, Haddad F, Qin A X, Baldwin K M

Abstract excerpt

Denervation (DEN) of rat soleus is associated with a decreased expression of slow type I myosin heavy chain (MHC) and an increased expression of the faster MHC isoforms. The molecular mechanisms behind these shifts remain unclear. We first investigated endogenous transcriptional activity of the type I MHC gene in normal and denervated soleus muscles via pre-mRNA analysis. Our results suggest that the type I MHC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Weight
Share to Denervation
Share to Genes, Regulator

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Myosin Heavy Chains

Share to Myosin Type I

Share to Myosin Type II

Share to Organ Size

Share to Rats, Sprague-Dawley

Source

Identifiers

PMID: 12444021
DOI: 10.1152/ajpcell.00389.2002

Genes

TEF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional regulation of the type I myosin heavy chain gene in denervated rat soleus.PMID 12444021Read ↗

Transcriptional regulation of the type I myosin heavy chain promoter in inactive rat soleus.Semantic proximity Read ↗

Transcriptional regulation of the myosin heavy chain IIb gene in inactive rat soleus.Semantic proximity Read ↗

Transcriptional control of muscle plasticity: differential regulation of troponin I genes by electrical activity.Semantic proximity Read ↗

Evidence of MyomiR network regulation of beta-myosin heavy chain gene expression during skeletal muscle atrophy.Semantic proximity Read ↗

Divergence in species and regulatory role of beta -myosin heavy chain proximal promoter muscle-CAT elements.Semantic proximity Read ↗

Myocyte enhancer factor-2 and serum response factor binding elements regulate fast Myosin heavy chain transcription in vivo.Semantic proximity Read ↗

Segregated regulatory elements direct beta-myosin heavy chain expression in response to altered muscle activity.Semantic proximity Read ↗

Differential expression of muscle regulatory factor genes in normal and denervated adult rat hindlimb muscles.Semantic proximity Read ↗

Inhibition of ryanodine receptor 1 in fast skeletal muscle fibers induces a fast-to-slow muscle fiber type transition.Semantic proximity Read ↗

Differential epigenetic modifications of histones at the myosin heavy chain genes in fast and slow skeletal muscle fibers and in response to muscle unloading.Semantic proximity Read ↗

Proximal sequences of the aldolase A fast muscle-specific promoter direct nerve- and activity-dependent expression in transgenic mice.Semantic proximity Read ↗

An E-box within the MHC IIB gene is bound by MyoD and is required for gene expression in fast muscleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.