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Article

Transcriptional regulation of the myosin heavy chain IIb gene in inactive rat soleus.

Muscle & nerve - 1 Sept 2009

McCall Gary E, Haddad Fadia, Roy Roland R, Zhong Hui, Edgerton V Reggie, Baldwin Kenneth M

Abstract excerpt

The myosin heavy chain (MHC) isoform composition of skeletal muscle is dependent, in part, on the functional demands of the muscle. The rat soleus muscle primarily expresses the slow-contracting type I MHC; however, chronic inactivity increases expression of the faster-contracting type II MHC isoforms. The purpose of this study was to identify the type IIb MHC promoter region(s) that regulate de novo...

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Identifiers

PMID: 19623632
DOI: 10.1002/mus.21361
PMCID: PMC2907261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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