Article
Differential epigenetic modifications of histones at the myosin heavy chain genes in fast and slow skeletal muscle fibers and in response to muscle unloading.
American journal of physiology. Cell physiology - 1 Jul 2009
Pandorf Clay E, Haddad Fadia, Wright Carola, Bodell Paul W, Baldwin Kenneth M
Abstract excerpt
Recent advances in chromatin biology have enhanced our understanding of gene regulation. It is now widely appreciated that gene regulation is dependent upon post-translational modifications to the histones which package genes in the nucleus of cells. Active genes are known to be associated with acetylation of histones (H3ac) and trimethylation of lysine 4 in histone H3 (H3K4me3). Using chromatin...
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