Article
Proximal sequences of the aldolase A fast muscle-specific promoter direct nerve- and activity-dependent expression in transgenic mice.
The Journal of biological chemistry - 12 Jun 1998
Spitz F, De Vasconcelos Z A, Châtelet F, Demignon J, Kahn A, Mira J C, Maire P, Daegelen D
Abstract excerpt
Muscle activity is known to modulate the muscle fiber phenotype. Changes in muscle activity (normal or experimentally induced) lead to modifications of the expression status of several muscle-specific genes. However, the transcription regulatory elements involved in the adaptative response are mainly unknown. The aldolase A muscle-specific promoter, pM, is expressed in adult fast twitch muscle with a preferential...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
