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Article

Genetics of variation in HDL cholesterol in humans and mice.

Circulation research - 7 Jan 2005

Wang Xiaosong, Paigen Beverly

Abstract excerpt

Plasma high-density lipoprotein cholesterol (HDL-C) concentrations are genetically determined to a great extent, and quantitative trait locus (QTL) analysis has been used to identify chromosomal regions containing genes regulating HDL-C levels. We discuss new genes found to participate in HDL metabolism. We also summarize 37 mouse and 30 human QTLs for plasma HDL-C levels, finding that all but three of the mouse...

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Identifiers

PMID: 15637305
DOI: 10.1161/01.RES.0000151332.39871.13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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