Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of promoter variants in baboon endothelial lipase that regulate high-density lipoprotein cholesterol levels.

Circulation - 4 Sept 2007

Cox Laura A, Birnbaum Shifra, Mahaney Michael C, Rainwater David L, Williams Jeff T, VandeBerg John L

Abstract excerpt

BACKGROUND: High-density lipoprotein cholesterol (HDL) levels are a major risk factor for cardiovascular disease. Previously we identified a quantitative trait locus on baboon chromosome 18 that regulates HDL. From positional cloning studies and expression studies, we identified the endothelial lipase gene (LIPG) as the primary candidate gene for the quantitative trait locus. The mechanism by which LIPG variation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cholesterol, HDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelium, Vascular

Share to Lipase

Share to Molecular Sequence Data

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 17709635
DOI: 10.1161/CIRCULATIONAHA.107.704346

Genes

LIPG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of promoter variants in baboon endothelial lipase that regulate high-density lipoprotein cholesterol levels.PMID 17709635Read ↗

Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels.Semantic proximity Read ↗

Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol.Semantic proximity Read ↗

Association of endothelial lipase gene (LIPG) haplotypes with high-density lipoprotein cholesterol subfractions and apolipoprotein AI plasma levels in Japanese Americans.Semantic proximity Read ↗

LIPC variants in the promoter and intron 1 modify HDL-C levels in a sex-specific fashion.Semantic proximity Read ↗

Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans.Semantic proximity Read ↗

Identification of candidate genes regulating HDL cholesterol using a chromosomal region expression array.Semantic proximity Read ↗

Identification of genetic variants in endothelial lipase in persons with elevated high-density lipoprotein cholesterol.Semantic proximity Read ↗

Sequencing of lipoprotein lipase gene in the Mediterranean river buffalo identified novel variants affecting gene expression.Semantic proximity Read ↗

Polymorphisms in the hepatic lipase gene affect plasma HDL-cholesterol levels in a Turkish population.Semantic proximity Read ↗

A novel variant associated with HDL-C levels by modifying DAGLB expression levels: An annotation-based genome-wide association study.Semantic proximity Read ↗

Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus.Semantic proximity Read ↗

Hepatic lipase (LIPC) sequencing in individuals with extremely high and low high-density lipoprotein cholesterol levels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.