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Article

Structure of prokaryotic SECIS mRNA hairpin and its interaction with elongation factor SelB.

Journal of molecular biology - 15 Nov 2002

Fourmy Dominique, Guittet Eric, Yoshizawa Satoko

Abstract excerpt

In prokaryotes, the recoding of a UGA stop codon as a selenocysteine codon requires a special elongation factor (EF) SelB and a stem-loop structure within the mRNA called a selenocysteine insertion sequence (SECIS). Here, we used NMR spectroscopy to determine the solution structure of the SECIS mRNA hairpin and characterized its interaction with the mRNA-binding domain of SelB. Our structural and biochemical data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12421564
DOI: 10.1016/s0022-2836(02)01030-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structure of prokaryotic SECIS mRNA hairpin and its interaction with elongation factor SelB.PMID 12421564Read ↗

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