Article
The bulged nucleotide in the Escherichia coli minimal selenocysteine insertion sequence participates in interaction with SelB: a genetic approach.
Journal of bacteriology - 1 Nov 2000
Li C, Reches M, Engelberg-Kulka H
Abstract excerpt
The UGA codon, which usually acts as a stop codon, can also direct the incorporation into a protein of the amino acid selenocysteine. This UGA decoding process requires a cis-acting mRNA element called the selenocysteine insertion sequence (SECIS), which can form a stem-loop structure. In Escherichia coli, selenocysteine incorporation requires only the 17-nucleotide-long upper stem-loop structure of the fdhF...
Topics
- Bacterial Proteins
- DNA Transposable Elements
- Escherichia coli
- Formate Dehydrogenases
- Hydrogenase
- Multienzyme Complexes
- Mutation
- Nucleic Acid Conformation
- Peptide Elongation Factors
- RNA-Binding Proteins
- Selenocysteine
- Uracil Nucleotides