Article
Specific p53 immunostaining patterns are associated with smoking habits in patients with oral squamous cell carcinomas.
Journal of clinical pathology - 1 Nov 2002
Cruz I, Snijders P J F, Van Houten V, Vosjan M, Van der Waal I, Meijer C J L M
Abstract excerpt
AIMS: To identify immunostaining patterns that are predictive for p53 mutations and to investigate whether p53 mutations are associated with established risk factors for oral squamous cell carcinoma (OSCC). METHODS: Fifty five OSCCs were investigated for p53 protein expression by immunohistochemistry (IHC). Ten of these cases, including five p53 immunopositive and five p53 immunonegative cases, were subjected to...
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