Article
Human papillomavirus expression and p53 gene mutations in squamous cell carcinoma.
Archives of otolaryngology--head & neck surgery - 1 Nov 1997
Portugal L G, Goldenberg J D, Wenig B L, Ferrer K T, Nodzenski E, Sabnani J B, Javier C, Weichselbaum R R, Vokes E E
Abstract excerpt
OBJECTIVES: To determine the incidence of human papillomavirus (HPV) infection and p53 gene mutation expression in squamous cell carcinomas (SCCs) of the oral cavity and tonsils, to correlate the presence of HPV and p53 gene mutation with known clinical and pathological features of SCC, and to determine whether infection with HPV or the presence of p53 gene mutations are independent prognosticators of patient...
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