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Article

TP53 and CDKN2a mutations in never-smoker oral tongue squamous cell carcinoma.

The Laryngoscope - 1 Jul 2014

Heaton Chase M, Durr Megan L, Tetsu Osamu, van Zante Annemieke, Wang Steven J

Abstract excerpt

OBJECTIVES/HYPOTHESIS: To determine the incidence and clinical significance of TP53 and CDKN2a somatic mutations in never smokers with oral tongue squamous cell carcinoma (OTSCC). STUDY DESIGN: Case series. METHODS: Fifty-one paraffin-embedded tumors from never smokers with OTSCC were obtained. p53 and p16 expression was determined by immunohistochemical (IHC) staining. Tumor DNA was amplified by polymerase chain...

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Share to Carcinoma, Squamous Cell
Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24431303
DOI: 10.1002/lary.24595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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