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Article

Increased susceptibility of the left compared to the right ventricle to remote ischemia/reperfusion injury in human C1-inhibitor-overexpressing transgene mice.

Journal of investigative surgery : the official journal of the Academy of Surgical Research - 1 Jan 2000

Grünenfelder Jürg, Inderbitzin Daniel, Zünd Gregor, Avital Itzhak, Burkhardt Tobias, Candinas Daniel, Turina Marko

Abstract excerpt

Acute myocardial injury has been demonstrated as a remote sequela of severe lower torso ischemia-reperfusion (I/R) due to proinflammatory events. In a model of I/R injury, administration of C1 esterase inhibitor (C1-Inh) reduces myocardial necrosis. We investigated the susceptibility of the left (LV) versus right ventricle (RV) and the protective effect of transgenic C1-Inh-overexpressing mice. Two groups of mice...

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PMID: 12396432
DOI: 10.1080/08941930290086065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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