Article
Genetic susceptibility to renal ischemia reperfusion injury revealed in a murine model.
Transplantation - 15 Mar 2000
Burne M J, Haq M, Matsuse H, Mohapatra S, Rabb H
Abstract excerpt
BACKGROUND: The development of genetically engineered mice has led to increased use of mouse models to study renal ischemic reperfusion injury (IRI). We hypothesized that susceptibility to IRI could result from strain differences due to genetic factors. METHODS: Our study compared recovery subsequent to renal IRI in NIH Swiss, C57BL/6, and BALB/c mice. Serum creatinine (SCr) and blood urea nitrogen (BUN) levels...
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