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Article

Linkage and association analysis of angiotensin I-converting enzyme (ACE)-gene polymorphisms with ACE concentration and blood pressure.

American journal of human genetics - 1 May 2001

Zhu X, Bouzekri N, Southam L, Cooper R S, Adeyemo A, McKenzie C A, Luke A, Chen G, Elston R C, Ward R

Abstract excerpt

Considerable effort has been expended to determine whether the gene for angiotensin I-converting enzyme (ACE) confers susceptibility to cardiovascular disease. In this study, we genotyped 13 polymorphisms in the ACE gene in 1,343 Nigerians from 332 families. To localize the genetic effect, we first performed linkage and association analysis of all the markers with ACE concentration. In multipoint...

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Identifiers

PMID: 11283791
DOI: 10.1086/320104
PMCID: PMC1226095

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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