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Article

High resolution MIC genotyping: design and application to the investigation of inflammatory bowel disease susceptibility.

Tissue antigens - 1 Aug 2002

Ahmad T, Marshall S E, Mulcahy-Hawes K, Orchard T, Crawshaw J, Armuzzi A, Neville M, van Heel D, Barnardo M, Welsh K I, Jewell D P, Bunce M

Abstract excerpt

The highly polymorphic nonclassical MHC class I chain-related (MIC) genes MICA and MICB encode stress inducible glycoproteins expressed on a variety of epithelial cells including intestinal cells. Interaction with the receptor NKG2D is likely to provide an important costimulatory signal for activation and proliferation of NK cells, activated macrophages and CD8 alphabeta and gammadelta T cells. Fifty-four MICA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12392511
DOI: 10.1034/j.1399-0039.2002.600207.x

Genes

MICA
MICB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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High resolution MIC genotyping: design and application to the investigation of inflammatory bowel disease susceptibility.PMID 12392511Read ↗

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High population frequencies of MICA copy number variations originate from independent recombination eventsSemantic proximity Read ↗

Population study of allelic diversity in the human MHC class I-related MIC-A gene.Semantic proximity Read ↗

Further polymorphism of the MICA gene.Semantic proximity Read ↗

Sequencing-based genotyping and association analysis of the MICA and MICB genes in type 1 diabetes.Semantic proximity Read ↗

Variation in MICA and MICB genes and enhanced susceptibility to paucibacillary leprosy in South India.Semantic proximity Read ↗

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