Article
MICA, MICB and C1_4_1 polymorphism in Crohn's disease and ulcerative colitis.
Tissue antigens - 1 Oct 2001
Glas J, Martin K, Brünnler G, Kopp R, Folwaczny C, Weiss E H, Albert E D
Abstract excerpt
MICA and MICB belong to a multicopy gene family located in the major histocompatibility complex (MHC) class I region near the HLA-B gene. They encode for MHC class I molecules, which are induced by stress factors like infection, heat shock or neoplastic transformation and which are mainly expressed on gastrointestinal epithelium. They are recognized by gammadelta T lymphocytes and natural killer (NK) cells....
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