Article
High resolution molecular phototyping of MICA and MICB alleles using sequence specific primers.
Human immunology - 1 Sept 2002
Collins Robert W M, Stephens Henry A F, Clare Michael A, Vaughan Robert W
Abstract excerpt
Major histocompatibility complex (MHC) class I chain-related genes, MICA and MICB, are located centromeric to human leukocyte antigen B (HLA-B) on chromosome 6. In response to stress stimuli, MIC is expressed on epithelial, endothelial and fibroblast cells, but not lymphocytes and has been demonstrated to ligate the natural killer (NK) cell receptor, NKG2D. Nucleotide sequences of MICA and MICB are highly...
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