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Article

High-throughput genotyping of HLA-G, HLA-F, MICA, and MICB and analysis of frequency distributions in healthy blood donors from Catalonia.

HLA - 1 May 2021

Closa Laia, Vidal Francisco, Herrero Maria J, Caro Jose L

Abstract excerpt

Similarly to HLA class I molecules, certain non-classical HLA class I genes and MHC class I polypeptide-related sequences A and B (MICA and MICB) act as ligands for KIR and NKG2D natural killer receptors. Although these genes are less polymorphic than HLA class I, few studies have analyzed their association with diseases. Information on allele frequencies in healthy donors is needed to map their distribution...

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PMID: 33599111
DOI: 10.1111/tan.14221

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