Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequencing-based genotyping and association analysis of the MICA and MICB genes in type 1 diabetes.

Diabetes - 1 Jun 2008

Field Sarah F, Nejentsev Sergey, Walker Neil M, Howson Joanna M M, Godfrey Lisa M, Jolley Jennifer D, Hardy Matthew P A, Todd John A

Abstract excerpt

OBJECTIVE: The nonclassical major histocompatibility complex (MHC) class I chain-related molecules (MICs), encoded within the MHC, function in immunity. The transmembrane polymorphism in MICA (MICA-STR) has been reported to be associated with type 1 diabetes. In this study, we directly sequenced both of the highly polymorphic MIC genes (MICA and MICB) in order to establish whether they are associated with type 1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 1
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-D Antigens

Share to HLA-DQ Antigens

Share to HLA-DQ beta-Chains

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Reference Values

Source

Identifiers

PMID: 18332098
DOI: 10.2337/db07-1402

Genes

MICA
MICB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequencing-based genotyping and association analysis of the MICA and MICB genes in type 1 diabetes.PMID 18332098Read ↗

Complete HLA genotyping of type 1 diabetes patients and controls from Mali reveals both expected and novel disease associations.Semantic proximity Read ↗

MICA gene polymorphism in the pathogenesis of type 1 diabetes.Semantic proximity Read ↗

MICA polymorphism is associated with type 1 diabetes in the Korean population.Semantic proximity Read ↗

Allelic variants of the human MHC class I chain-related B gene (MICB).Semantic proximity Read ↗

MICA marks additional risk factors for Type 1 diabetes on extended HLA haplotypes: an association and meta-analysis.Semantic proximity Read ↗

Definition of high-risk type 1 diabetes HLA-DR and HLA-DQ types using only three single nucleotide polymorphisms.Semantic proximity Read ↗

High-throughput genotyping of HLA-G, HLA-F, MICA, and MICB and analysis of frequency distributions in healthy blood donors from Catalonia.Semantic proximity Read ↗

Association of MHC Class I chain-related A (MIC-A) gene polymorphism with Type I diabetesSemantic proximity Read ↗

Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases.Semantic proximity Read ↗

Polymorphism in the transmembrane region of the MICA gene and type 1 diabetes.Semantic proximity Read ↗

High resolution MIC genotyping: design and application to the investigation of inflammatory bowel disease susceptibility.Semantic proximity Read ↗

Advances in MICA genotyping: characterization of 406 novel alleles and their frequencies in multiple populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.