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Article

Variation in MICA and MICB genes and enhanced susceptibility to paucibacillary leprosy in South India.

Human molecular genetics - 1 Oct 2006

Tosh Kerrie, Ravikumar Muthuswamy, Bell Jordana Tzenova, Meisner Sarah, Hill Adrian V S, Pitchappan Ramasamy

Abstract excerpt

In a study of mainly paucibacillary leprosy-affected sib-pair families from South India, in addition to the expected associations with the HLA-DRB1 locus, we have identified significant association with a functional variant of the MICA gene as well as a microsatellite in the flanking region of the MICB gene. The associations with MICA and MICB cannot be accounted for by linkage disequilibrium with the HLA class...

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Source

Identifiers

PMID: 16923796
DOI: 10.1093/hmg/ddl229

Genes

MICA
MICB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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