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Article

Inactivation of the F4/80 glycoprotein in the mouse germ line.

Molecular and cellular biology - 1 Nov 2002

Schaller Evelyne, Macfarlane Alison J, Rupec Rudolf A, Gordon Siamon, McKnight Andrew J, Pfeffer Klaus

Abstract excerpt

Macrophages play a crucial role in the defense against pathogens. Distinct macrophage populations can be defined by the expression of restricted cell surface proteins. Resident tissue macrophages, encompassing Kupffer cells of the liver and red pulp macrophages of the spleen, characteristically express the F4/80 molecule, a cell surface glycoprotein related to the seven transmembrane-spanning family of hormone...

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Identifiers

PMID: 12391169
DOI: 10.1128/MCB.22.22.8035-8043.2002
PMCID: PMC134735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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