Article
Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor.
The Journal of experimental medicine - 15 Feb 1999
Gao J L, Lee E J, Murphy P M
Abstract excerpt
N-formylpeptides derive from bacterial and mitochondrial proteins, and bind to specific receptors on mammalian phagocytes. Since binding induces chemotaxis and activation of phagocytes in vitro, it has been postulated that N-formylpeptide receptor signaling in vivo may be important in antimicrobi...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
