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Article

F4/80: the macrophage-specific adhesion-GPCR and its role in immunoregulation.

Advances in experimental medicine and biology - 1 Jan 2010

Lin Hsi-Hsien, Stacey Martin, Stein-Streilein Joan, Gordon Siamon

Abstract excerpt

As a macrophage-restricted reagent, the generation and application of the F4/80 mAb has greatly benefited the phenotypic characterization of mouse tissue macrophages for three decades. Following the molecular identification of the F4/80 antigen as an EGF-TM7 member of the adhesion-GPCR family, great interest was ignited to understand its cell type-specific expression pattern as well as its functional role in...

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Share to Antigens, Differentiation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, G-Protein-Coupled

Source

Identifiers

PMID: 21618834
DOI: 10.1007/978-1-4419-7913-1_13

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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