Article
Conditional gene targeting in macrophages and granulocytes using LysMcre mice.
Transgenic research - 1 Aug 1999
Clausen B E, Burkhardt C, Reith W, Renkawitz R, Förster I
Abstract excerpt
Conditional mutagenesis in mice has recently been made possible through the combination of gene targeting techniques and site-directed mutagenesis, using the bacteriophage P1-derived Cre/loxP recombination system. The versatility of this approach depends on the availability of mouse mutants in which the recombinase Cre is expressed in the appropriate cell lineages or tissues. Here we report the generation of mice...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
