Localization of lens intrinsic membrane protein MP19 and mutant protein MP19(To3) using fluorescent expression vectors.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Localization of lens intrinsic membrane protein MP19 and mutant protein MP19(To3) using fluorescent expression vectors.

Molecular vision - 11 Oct 2002

Chen Tong, Li XiaLian, Yang Yu, Church Robert L

Abstract excerpt

PURPOSE: [corrected] MP19 is the second most abundant major intrinsic protein of the lens fiber cell membrane. A specific heritable mutation at amino acid 15 in the MP19 protein, termed MP19To3, results in total cataract and microphthalmia in the mouse. The goals of this study were to determine the specific localization of MP19 in the cell membrane and to determine whether the mutant MP19To3 protein migrates to...

Topics

Animals
Biological Transport
Cataract
Cell Line
Cell Membrane
Chick Embryo
Epithelial Cells
Eye Proteins
Genetic Vectors
Green Fluorescent Proteins
Humans
Lens, Crystalline
Luminescent Proteins
Membrane Glycoproteins
Membrane Proteins
Microphthalmos
Mutation
Recombinant Fusion Proteins

Source

Open in PubMed

Identifiers

PMID: 12379840

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics