Article
Disruption of lens fiber cell architecture in mice expressing a chimeric AQP0-LTR protein.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 2000
Shiels A, Mackay D, Bassnett S, Al-Ghoul K, Kuszak J
Abstract excerpt
Aquaporin-0 (AQP0) is the major intrinsic protein of lens fiber cells and the founder member of the water channel gene family. Here we show that disruption of the AQP0 gene by an early transposon (ETn) element results in expression of a chimeric protein, comprised of approximately 75% AQP0 and ap...
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