Article
Topogenesis of a nucleolar protein: determination of molecular segments directing nucleolar association.
Molecular biology of the cell - 1 Feb 1997
Zirwes R F, Kouzmenko A P, Peters J M, Franke W W, Schmidt-Zachmann M S
Abstract excerpt
To identify the element(s) in nucleolar proteins which determine nucleolus-specific topogenesis, we have used different kinds of cDNA constructs encoding various chimeric combinations of mutants of the constitutive nucleolar protein NO38 (B23): 1) with an amino terminally placed short "myc tag"; 2) with two different carboxyl terminally attached large alpha-helical coiled coil structures, the lamin A rod domain...
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