Article
PKC putative phosphorylation site Ser235 is required for MIP/AQP0 translocation to the plasma membrane.
Molecular vision - 29 May 2008
Golestaneh Nady, Fan Jianguo, Zelenka Peggy, Chepelinsky Ana B
Abstract excerpt
PURPOSE: To investigate the functional significance of MIP/AQP0 phosphorylation at serine(235). METHODS: MIP/AQP0 expression and cellular localization was studied in rat lens epithelia explants induced to differentiate by FGF-2. MIP wild type (WT) and MIP (S235A) mutant expression plasmids were constructed and transiently expressed in RK13 cells. Subcellular localization of endogenous MIP in differentiating lens...
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