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Article

Methylpurine DNA glycosylase of the hyperthermophilic archaeon Archaeoglobus fulgidus.

Biochemistry - 22 Oct 2002

Birkeland Nils-Kåre, Anensen Hilde, Knaevelsrud Ingeborg, Kristoffersen Wenche, Bjørås Magnar, Robb Frank T, Klungland Arne, Bjelland Svein

Abstract excerpt

Base excision repair of DNA alkylation damage is initiated by a methylpurine DNA glycosylase (MPG) function. Such enzymes have previously been characterized from bacteria and eukarya, but not from archaea. We identified activity for the release of methylated bases from DNA in cell-free extracts o...

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Identifiers

PMID: 12379112
DOI: 10.1021/bi020334w

Genes

MPG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12379112-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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