Release of normal bases from intact DNA by a native DNA repair enzyme.

doi:10.1093/emboj/17.2.363

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Article

Release of normal bases from intact DNA by a native DNA repair enzyme.

The EMBO journal - 15 Jan 1998

Berdal K G, Johansen R F, Seeberg E

Abstract excerpt

Base excision repair is initiated by DNA glycosylases removing inappropriate bases from DNA. One group of these enzymes, comprising 3-methyladenine DNA glycosylase II (AlkA) from Escherichia coli and related enzymes from other organisms, has been found to have an unusual broad specificity towards...

Topics

Base Composition
DNA
DNA Glycosylases
DNA Repair
Escherichia coli
Gene Expression Regulation, Bacterial
Guanine
Humans
Hydrogen-Ion Concentration
Mutation
N-Glycosyl Hydrolases
Saccharomyces cerevisiae

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