Article
Release of normal bases from intact DNA by a native DNA repair enzyme.
The EMBO journal - 15 Jan 1998
Berdal K G, Johansen R F, Seeberg E
Abstract excerpt
Base excision repair is initiated by DNA glycosylases removing inappropriate bases from DNA. One group of these enzymes, comprising 3-methyladenine DNA glycosylase II (AlkA) from Escherichia coli and related enzymes from other organisms, has been found to have an unusual broad specificity towards quite different base structures. We tested whether such enzymes might also be capable of removing normal base residues...
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