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Article

Thermostable repair enzyme for oxidative DNA damage from extremely thermophilic bacterium, Thermus thermophilus HB8.

Nucleic acids research - 15 Feb 1998

Mikawa T, Kato R, Sugahara M, Kuramitsu S

Abstract excerpt

The mutM (fpg) gene, which encodes a DNA glycosylase that excises an oxidatively damaged form of guanine, was cloned from an extremely thermophilic bacterium, Thermus thermophilus HB8. Its nucleotide sequence encoded a 266 amino acid protein with a molecular mass of approximately 30 kDa. Its predicted amino acid sequence showed 42% identity with the Escherichia coli protein. The amino acid residues Cys, Asn, Gln...

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Identifiers

PMID: 9461446
DOI: 10.1093/nar/26.4.903
PMCID: PMC147369

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Thermostable repair enzyme for oxidative DNA damage from extremely thermophilic bacterium, Thermus thermophilus HB8.PMID 9461446Read ↗

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