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Article

Real-time studies of conformational dynamics of the repair enzyme E. coli formamidopyrimidine-DNA glycosylase and its DNA complexes during catalytic cycle.

Mutation research - 1 Mar 2010

Koval Vladimir V, Kuznetsov Nikita A, Ishchenko Alexander A, Saparbaev Murat K, Fedorova Olga S

Abstract excerpt

Fpg protein from Escherichia coli belongs to the class of DNA glycosylases/abasic site lyases excising several oxidatively damaged purines in the base excision repair pathway. In this review, we summarize the results of our studies of Fpg protein from E. coli, elucidating the intrinsic mechanism of recognition and excision of damaged bases in DNA.

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Identifiers

PMID: 19751748
DOI: 10.1016/j.mrfmmm.2009.08.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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