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Article

A new member of the endonuclease III family of DNA repair enzymes that removes methylated purines from DNA.

Current biology : CB - 17 Jun 1999

Begley T J, Haas B J, Noel J, Shekhtman A, Williams W A, Cunningham R P

Abstract excerpt

DNA is constantly exposed to endogenous andexogenous alkylating agents that can modify its bases,resulting in mutagenesis in the absence of DNA repair [1,2]. Alkylation damage is removed by the action of DNA glycosylases, which initiate the base excision repair pathway and protect the sequence information of the genome [3-5]. We have identified a new class of methylpurine DNA glycosylase, designated MpgII, that...

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Identifiers

PMID: 10375529
DOI: 10.1016/s0960-9822(99)80288-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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