Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Site-directed integration of the cre gene mediated by Cre recombinase using a combination of mutant lox sites.

Nucleic acids research - 1 Oct 2002

Araki Kimi, Araki Masatake, Yamamura Ken-ichi

Abstract excerpt

The Cre-lox system is an important tool for genetic manipulation. To promote integrative reactions, two strategies using mutant lox sites have been developed. One is the left element/right element (LE/RE)-mutant strategy and the other is the cassette exchange strategy using heterospecific lox sites such as lox511 or lox2272. We compared the recombination efficiencies using these mutant lox sites in embryonic stem...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Integrases
Share to Mice, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Mutagenesis, Site-Directed

Share to Plasmids

Share to Recombination, Genetic

Share to Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 12364620
DOI: 10.1093/nar/gnf102
PMCID: PMC140563

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Site-directed integration of the cre gene mediated by Cre recombinase using a combination of mutant lox sites.PMID 12364620Read ↗

Comparative analysis of right element mutant lox sites on recombination efficiency in embryonic stem cells.Semantic proximity Read ↗

Site-specific recombination of asymmetric lox sites mediated by a heterotetrameric Cre recombinase complex.Semantic proximity Read ↗

Large-Scale Genome-Wide Optimization and Prediction of the Cre Recombinase System for Precise Genome Manipulation in MiceSemantic proximity Read ↗

Large-Scale Genome-Wide Optimization and Prediction of the Cre Recombinase System for Precise Genome Manipulation in MiceSemantic proximity Read ↗

Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells.Semantic proximity Read ↗

Generation of a series of knock-in alleles using RMCE in ES cells.Semantic proximity Read ↗

PCR-based strategy for genotyping mice and ES cells harboring loxP sites.Semantic proximity Read ↗

Mutational analysis of loxP sites for efficient Cre-mediated insertion into genomic DNA.Semantic proximity Read ↗

Exchangeable gene trap using the Cre/mutated lox system.Semantic proximity Read ↗

Mammalian genome targeting using site-specific recombinases.Semantic proximity Read ↗

A genetic screen identifies novel non-compatible loxP sites.Semantic proximity Read ↗

Overview of gene targeting by homologous recombination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.