Article
Comparative analysis of right element mutant lox sites on recombination efficiency in embryonic stem cells.
BMC biotechnology - 31 Mar 2010
Araki Kimi, Okada Yuka, Araki Masatake, Yamamura Ken-ichi
Abstract excerpt
BACKGROUND: Cre-mediated site-specific integrative recombination in mouse embryonic stem (ES) cells is a useful tool for genome engineering, allowing precise and repeated site-specific integration. To promote the integrative reaction, a left element/right element (LE/RE) mutant strategy using a p...
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