Expression and localization of P-glycoprotein in human heart: effects of cardiomyopathy.

doi:10.1177/002215540205001008

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Article

Expression and localization of P-glycoprotein in human heart: effects of cardiomyopathy.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Oct 2002

Meissner Konrad, Sperker Bernhard, Karsten Christiane, Meyer Zu Schwabedissen Henriette, Seeland Ute, Böhm Michael, Bien Sandra, Dazert Peter, Kunert-Keil Christiane, Vogelgesang Silke, Warzok Rolf, Siegmund Werner, Cascorbi Ingolf, Wendt Michael, Kroemer Heyo K

Abstract excerpt

ABC-type transport proteins, such as P-glycoprotein (P-gp), modify intracellular concentrations of many substrate compounds. They serve as functional barriers against entry of xenobiotics (e.g., in the gut or the blood-brain barrier) or contribute to drug excretion. Expression of transport proteins in the heart could be an important factor modifying cardiac concentrations of drugs known to be transported by P-gp...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12364568
DOI: 10.1177/002215540205001008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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