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Article

Expression and localization of the multidrug resistance protein 5 (MRP5/ABCC5), a cellular export pump for cyclic nucleotides, in human heart.

The American journal of pathology - 1 Oct 2003

Dazert Peter, Meissner Konrad, Vogelgesang Silke, Heydrich Björn, Eckel Lothar, Böhm Michael, Warzok Rolf, Kerb Reinhold, Brinkmann Ulrich, Schaeffeler Elke, Schwab Matthias, Cascorbi Ingolf, Jedlitschky Gabriele, Kroemer Heyo K

Abstract excerpt

The multidrug resistance protein 5 (MRP5/ABCC5) has been recently identified as cellular export pump for cyclic nucleotides with 3',5'-cyclic GMP (cGMP) as a high-affinity substrate. In view of the important role of cGMP for cardiovascular function, expression of this transport protein in human heart is of relevance. We analyzed the expression and localization of MRP5 in human heart [21 auricular (AS) and 15 left...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14507663
DOI: 10.1016/S0002-9440(10)63513-4
PMCID: PMC1868287

Genes

ABCC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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