Article

Effects of Acute and Chronic Gabapentin Treatment on Cardiovascular Function of Rats

2023-10-13

Abstract excerpt

Gabapentin (GBP), a GABA analogue, is primarily used as an anticonvulsant to treat partial seizures and neuropathic pain. While a majority of the side effects are associated with the nervous system, emerging evidence suggests a high risk for heart diseases in the patients taking GBP. In the present study, we used a preclinical model of rats to investigate (1) the acute cardiovascular responses to GBP (bolus i.v. i...

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Literature Corpus work: 203ccd17-5647-511e-bfe5-abb44bfc6a65
DOI: 10.20944/preprints202310.0903.v1

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