[Pharmacological control of P-glycoprotein expression].

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Article

[Pharmacological control of P-glycoprotein expression].

Bulletin du cancer - 1 May 1994

Muller C, Bailly J D, Jaffrezou J P, Goubin F, Laurent G

Abstract excerpt

Calcium channel inhibitors, such as verapamil, have been identified as having the ability to modulate the multidrug-resistant (MDR) phenotype due to overexpression of P-glycoprotein (Pgp). We have studied the effect of verapamil on Pgp expression levels in a cell line originating from acute myelo...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Antineoplastic Agents
Calcium Channel Blockers
Dose-Response Relationship, Drug
Drug Resistance, Multiple
Drug Therapy, Combination
Gene Expression Regulation
Humans
Karyotyping
Models, Biological
Phenotype
RNA, Messenger
Time Factors
Tumor Cells, Cultured
Verapamil

Source

Open in PubMed

Identifiers

PMID: 7749215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7749215-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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