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Article

[Pharmacological control of P-glycoprotein expression].

Bulletin du cancer - 1 May 1994

Muller C, Bailly J D, Jaffrezou J P, Goubin F, Laurent G

Abstract excerpt

Calcium channel inhibitors, such as verapamil, have been identified as having the ability to modulate the multidrug-resistant (MDR) phenotype due to overexpression of P-glycoprotein (Pgp). We have studied the effect of verapamil on Pgp expression levels in a cell line originating from acute myeloblastic leukemia and resistant to adriamycin, K562/ADR. In this line, the addition of 15 microM verapamil in the...

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PMID: 7749215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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