Article
The ATP-binding cassette transporter ABCG2 (BCRP), a marker for side population stem cells, is expressed in human heart.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Feb 2006
Meissner Konrad, Heydrich Björn, Jedlitschky Gabriele, Meyer Zu Schwabedissen Henriette, Mosyagin Igor, Dazert Peter, Eckel Lothar, Vogelgesang Silke, Warzok Rolf W, Böhm Michael, Lehmann Christian, Wendt Michael, Cascorbi Ingolf, Kroemer Heyo K
Abstract excerpt
Efforts to improve severely impaired myocardial function include transplantation of autologous hematopoietic side population (SP) stem cells. The transmembrane ABC-type (ATP binding cassette) half-transporter ABCG2 (BCRP) serves as a marker protein for SP cell selection. We have recently shown that other ABC transport proteins such as ABCB1 and ABCC5 are differentially expressed in normal and diseased human...
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