Article
Colorimetric SNP analysis using oligonucleotide-modified nanoparticles.
Chemical communications (Cambridge, England) - 21 Sept 2002
Ihara Toshihiro, Chikaura Yasushi, Tanaka Shojiro, Jyo Akinori
Abstract excerpt
A point mutation in the p53 gene has been detected by means of fluorescence microscopy and fluorescent resonance energy transfer (FRET) through sequence selective aggregation of DNA-modified nanoparticles, in which fluorescent dyes were impregnated.
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