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Article

Gold-nanorod-based colorimetric and fluorescent approach for sensitive and specific assay of disease-related gene and mutation.

ACS applied materials & interfaces - 27 Nov 2013

Wang Wenhong, Zhao Yina, Jin Yan

Abstract excerpt

Sensitive and specific detection of disease-related gene and single nucleotide polymorphism (SNP) is of great importance in cancer diagnosis. Here, a colorimetric and fluorescent approach is described for detection of the p53 gene and SNP in homogeneous solution by using gold nanorods (GNRs) as both colorimetric probe and fluorescence quencher. Hairpin oligonucleotide was utilized as DNA probe to ensure highly...

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PMID: 24151993
DOI: 10.1021/am4034119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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