Rapid and label-free single-nucleotide discrimination via an integrative nanoparticle-nanopore approach.

Abstract excerpt

Single-nucleotide polymorphism (SNP) is an important biomarker for disease diagnosis, treatment monitoring, and development of personalized medicine. Recent works focused primarily on ultrasensitive detection, while the need for rapid and label-free single-nucleotide discrimination techniques, which are crucial criteria for translation into clinical applications, remains relatively unexplored. In this work, we...

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• Biosensing Techniques
• DNA
• DNA Mutational Analysis
• Equipment Design
• Nanoparticles
• Nanotechnology