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Article

Detection of p53 gene mutation by using a novel biosensor based on localized surface plasmon resonance.

Neoplasma - 1 Jan 2012

Duan R Q, Yuan J L, Yang H, Luo X G, Xi M R

Abstract excerpt

Few studies to date have reported on the development and application of a nanobiosensor based on localized surface plasmon resonance (LSPR) for detecting gene mutations. This study aimed to develop a novel LSPR biosensor used for detecting p53 mutation. Nanosphere lithography was used to fabricate the silver nanoparticles. The DNA probe was designed to recognize the target sequence and immobilized on the chip...

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Identifiers

PMID: 22329850
DOI: 10.4149/neo_2012_045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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