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Article

Gold nanoparticles-based biosensing of single nucleotide DNA mutations.

International journal of biological macromolecules - 1 Aug 2013

Polak Pazit, Zalevsky Zeev, Shefi Orit

Abstract excerpt

Detection of DNA mutations is critical for scientific research and diagnostic procedures. Here, we propose a novel interdisciplinary method for rapid and simple detection of DNA mutations. We show that heating a solution containing DNA and gold nanoparticles results in degradation of the DNA. Surprisingly, we found that the DNA can be protected against degradation, if an oligonucleotide that matches the DNA is...

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PMID: 23597712
DOI: 10.1016/j.ijbiomac.2013.04.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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