Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Link between the X4 phenotype in human immunodeficiency virus type 1-infected mothers and their children, despite the early presence of R5 in the child.

The Journal of infectious diseases - 1 Oct 2002

Casper Charlotte H E, Clevestig Peter, Carlenor Elisabeth, Leitner Thomas, Anzén Bo, Lidman Knut, Belfrage Erik, Albert Jan, Bohlin Ann-Britt, Navér Lars, Lindgren Susanne, Fenyö Eva Maria, Ehrnst Anneka C

Abstract excerpt

Coreceptor use was determined for human immunodeficiency virus type 1 (HIV-1) isolates of various subtypes from 11 women during pregnancy and their infected children. Isolates from peripheral blood mononuclear cells (n=79) and from plasma (n=59) were available. The clinical and immunological stages of HIV-1 infection were recorded. Coreceptor use was tested on human cell lines expressing CD4 and different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV-1
Share to HIV Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infectious Disease Transmission, Vertical

Share to Leukocytes, Mononuclear

Share to Pregnancy

Share to Pregnancy Complications, Infectious

Share to Receptors, CCR5

Share to Receptors, CXCR4

Source

Identifiers

PMID: 12232831
DOI: 10.1086/342948

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Link between the X4 phenotype in human immunodeficiency virus type 1-infected mothers and their children, despite the early presence of R5 in the child.PMID 12232831Read ↗

The X4 phenotype of HIV type 1 evolves from R5 in two children of mothers, carrying X4, and is not linked to transmission.Semantic proximity Read ↗

HIV-1 co-receptor usage: influence on mother-to-child transmission and pediatric infection.Semantic proximity Read ↗

HIV-1 with multiple CCR5/CXCR4 chimeric receptor use is predictive of immunological failure in infected children.Semantic proximity Read ↗

Coreceptor change appears after immune deficiency is established in children infected with different HIV-1 subtypes.Semantic proximity Read ↗

Flexible use of CCR5 in the absence of CXCR4 use explains the immune deficiency in HIV-1 infected children.Semantic proximity Read ↗

The role of genetic variants of Stromal cell-Derived Factor 1 in pediatric HIV-1 infection and disease progression.Semantic proximity Read ↗

HIV type 1 chemokine receptor usage in mother-to-child transmission.Semantic proximity Read ↗

High CD4(+) T-cell surface CXCR4 density as a risk factor for R5 to X4 switch in the course of HIV-1 infection.Semantic proximity Read ↗

Phenotype variation in human immunodeficiency virus type 1 transmission and disease progression.Semantic proximity Read ↗

R5 to X4 switch of the predominant HIV-1 population in cellular reservoirs during effective highly active antiretroviral therapy.Semantic proximity Read ↗

Genotypic and phenotypic characterization of viral isolates from HIV-1 subtype C-infected children with slow and rapid disease progression.Semantic proximity Read ↗

Changes in the HIV type 1 envelope gene from non-subtype B HIV type 1-infected children in Kenya.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.