Article
The X4 phenotype of HIV type 1 evolves from R5 in two children of mothers, carrying X4, and is not linked to transmission.
AIDS research and human retroviruses - 1 May 2005
Clevestig P, Maljkovic I, Casper C, Carlenor E, Lindgren S, Navér L, Bohlin A-B, Fenyö E M, Leitner T, Ehrnst A
Abstract excerpt
Previously, we found that emergence of the X4 viral phenotype in HIV-1-infected children was related to the presence of X4 in their mothers (C.H. Casper et al., J Infect Dis 2002; 186:914-921). Here, we investigated the origin of the X4 phenotype in the child, analyzing two mother-child pairs (Ma-Ca, Mb-Cb) where the mothers carried X4 and their children developed X4 after an initial presence of R5. We used...
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