Coreceptor change appears after immune deficiency is established in children infected with different HIV-1 subtypes.

doi:10.1089/088922202753519124

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Article

Coreceptor change appears after immune deficiency is established in children infected with different HIV-1 subtypes.

AIDS research and human retroviruses - 20 Mar 2002

Casper C, Navér L, Clevestig P, Belfrage E, Leitner T, Albert J, Lindgren S, Ottenblad C, Bohlin A-B, Fenyö E M, Ehrnst A

Abstract excerpt

Change of HIV-1 coreceptor use has been connected to progression of disease in children infected with HIV-1, presumably subtype B. It has not been possible to discern whether the appearance of new viral phenotypes precedes disease development or comes as a consequence of it. We studied the evolution of coreceptor use in HIV-1 isolates from 24 vertically infected children. Their clinical, virological, and...

Topics

Acquired Immunodeficiency Syndrome
Base Sequence
CD4 Lymphocyte Count
Cell Line
Child
Child, Preschool
Female
HIV-1
Humans
Infant
Infectious Disease Transmission, Vertical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukocytes, Mononuclear

Milk, Human

Phenotype

Phylogeny

Pregnancy

Prospective Studies

Receptors, Chemokine

Source

Open in PubMed

Identifiers

PMID: 11897036
DOI: 10.1089/088922202753519124

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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