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Article

Coreceptor change appears after immune deficiency is established in children infected with different HIV-1 subtypes.

AIDS research and human retroviruses - 20 Mar 2002

Casper C, Navér L, Clevestig P, Belfrage E, Leitner T, Albert J, Lindgren S, Ottenblad C, Bohlin A-B, Fenyö E M, Ehrnst A

Abstract excerpt

Change of HIV-1 coreceptor use has been connected to progression of disease in children infected with HIV-1, presumably subtype B. It has not been possible to discern whether the appearance of new viral phenotypes precedes disease development or comes as a consequence of it. We studied the evolution of coreceptor use in HIV-1 isolates from 24 vertically infected children. Their clinical, virological, and...

Read the complete abstract on PubMed

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Share to Acquired Immunodeficiency Syndrome
Share to CD4 Lymphocyte Count

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Infectious Disease Transmission, Vertical

Share to Leukocytes, Mononuclear

Share to Milk, Human

Share to Receptors, Chemokine

Share to Receptors, HIV

Share to Virus Replication

Source

Identifiers

PMID: 11897036
DOI: 10.1089/088922202753519124

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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