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Article

HIV-1 co-receptor usage: influence on mother-to-child transmission and pediatric infection.

Journal of translational medicine - 27 Jan 2011

Cavarelli Mariangela, Scarlatti Gabriella

Abstract excerpt

Viral CCR5 usage is not a predictive marker of mother to child transmission (MTCT) of HIV-1. CXCR4-using viral variants are little represented in pregnant women, have an increased although not significant risk of transmission and can be eventually also detected in the neonates. Genetic polymorphisms are more frequently of relevance in the child than in the mother. However, specific tissues as the placenta or the...

Topics

Disease Progression
Female
HIV Infections
HIV-1
Humans
Immune System
Intestines
Maternal Exposure
Mothers
Phenotype
Placenta
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pregnancy

Pregnancy Complications, Infectious

Receptors, HIV

Source

Open in PubMed Open full text

Identifiers

PMID: 21284900
DOI: 10.1186/1479-5876-9-S1-S10
PMCID: PMC3105501

Genes

CXCR4
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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