Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tissue-specific expression of p73 and p63 isoforms in human tissues

27 Jul 2021

Abstract excerpt

p73 and p63 are members of the p53 family that exhibit overlapping and distinct functions in development and homeostasis. The evaluation of p73 and p63 isoform expression across human tissue can provide greater insight to the functional interactions between family members. We determined the mRNA isoform expression patterns of TP73 and TP63 across a panel of 36 human tissues and protein expression within the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Cancer Research and Treatments
Share to Molecular Biology Techniques and Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34315849
DOI: 10.1038/s41419-021-04017-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tissue-specific expression of p73 and p63 isoforms in human tissuesPMID 34315849Read ↗

A global analysis of the complex landscape of isoforms and regulatory networks of p63 in human cells and tissuesSemantic proximity Read ↗

p63 and p73 in human cancer: defining the network.Semantic proximity Read ↗

The diverse oncogenic and tumour suppressor roles of p63 and p73 in cancer: a review by cancer site.Semantic proximity Read ↗

Mechanisms of Functional Pleiotropy of p73 in Cancer and BeyondSemantic proximity Read ↗

p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.Semantic proximity Read ↗

Distinct TP63 Isoform-Driven Transcriptional Signatures Predict Tumor Progression and Clinical Outcomes.Semantic proximity Read ↗

p53 Family: Role of Protein Isoforms in Human CancerSemantic proximity Read ↗

p63-related signaling at a glanceSemantic proximity Read ↗

TP53 family members and human cancers.Semantic proximity Read ↗

Biological functions of p53 isoforms through evolution: lessons from animal and cellular models.Semantic proximity Read ↗

Role of p53 family members p73 and p63 in human hematological malignanciesSemantic proximity Read ↗

The Δ133p53 Isoforms, Tuners of the p53 PathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.